Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.75 |
| ▸ | RAB9A | P51151 | 7/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456403 | 0.86 | RAB9A (1.00) | NPC1RAB9ANPSR1ALDH1A1LMNA | |
| SCHEMBL13162953 | 0.85 | MEN1 (0.69) | NPC1RAB9APKMALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL30416720 | 0.84 | MEN1 (0.67) | NPC1RAB9APKMALDH1A1KDM4E | |
| SCHEMBL14859988 | 0.81 | RAB9A (0.79) | NPC1RAB9ANPSR1PKMALDH1A1 | |
| SCHEMBL2682648 | 0.80 | RAB9A (1.00) | NPC1RAB9ANPSR1PKMALDH1A1 | |
| SCHEMBL2681235 | 0.79 | LMNA (0.70) | NPC1RAB9ANPSR1PKMALDH1A1 | |
| SCHEMBL28572242 | 0.79 | NPSR1 (0.60) | NPC1RAB9ANPSR1PKMALDH1A1 | |
| SCHEMBL5455495 | 0.78 | ALDH1A1 (0.72) | NPC1RAB9ANPSR1ALDH1A1KDM4E | |
| SCHEMBL14859928 | 0.76 | RAB9A (0.75) | NPC1RAB9ANPSR1PKMALDH1A1 | |
| SCHEMBL27474427 | 0.75 | NPC1 (0.63) | NPC1RAB9APKMALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |