Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451730 | 0.86 | NPC1 (0.75) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27726009 | 0.84 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5455495 | 0.80 | ALDH1A1 (0.72) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29331631 | 0.78 | RAB9A (0.75) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5448102 | 0.78 | ALDH1A1 (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3397939 | 0.76 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL841777 | 0.76 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9818531 | 0.75 | ALDH1A1 (0.77) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9728405 | 0.75 | ALDH1A1 (0.77) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3140037 | 0.75 | HPGD (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |