Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002382 | 0.84 | CHRM4 (0.58) | CHRM4SMN1; SMN2CYP2C19BRD4SLC18A3 | |
| SCHEMBL5460480 | 0.82 | FAAH (0.55) | CHRM4SMN1; SMN2BRD4SLC18A3ALDH1A1 | |
| SCHEMBL5447949 | 0.81 | DRD2 (0.51) | CHRM4ALDH1A1RAB9AL3MBTL1HTT | |
| SCHEMBL4035554 | 0.81 | SMN1; SMN2 (0.72) | CHRM4SMN1; SMN2CYP2C19ALDH1A1RAB9A | |
| SCHEMBL21159622 | 0.79 | BRD4 (0.61) | CHRM4SMN1; SMN2BRD4SLC18A3ALDH1A1 | |
| SCHEMBL5490962 | 0.78 | KCNH2 (0.56) | SMN1; SMN2SLC18A3ALDH1A1RAB9ANPC1 | |
| SCHEMBL8922008 | 0.78 | CHRM4 (0.59) | CHRM4SMN1; SMN2BRD4SLC18A3ALDH1A1 | |
| SCHEMBL28171449 | 0.77 | KCNH2 (0.52) | CHRM4SMN1; SMN2SLC18A3ALDH1A1RAB9A | |
| SCHEMBL31073550 | 0.77 | KCNH2 (0.56) | CHRM4SMN1; SMN2CYP2C19BRD4SLC18A3 | |
| Hydrochloric Acid SCHEMBL6195871 | 0.77 | KCNH2 (0.55) | SMN1; SMN2SLC18A3ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021405-A1 | ARYL- AND HETEROARYLPIPERIDINECARBOXYLATE-DERIVATIVES METHODS FOR THEIR PREPARATION AND USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021405-A1 | ARYL- AND HETEROARYLPIPERIDINECARBOXYLATE-DERIVATIVES METHODS FOR THEIR PREPARATION AND USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS | FAAH, FAAH2, HRH2 | CHRM4 1457/4885SMN1; SMN2 1268/4885CYP2C19 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.