Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138877 | 0.90 | ALDH1A1 (0.57) | BRD4ALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL4002382 | 0.82 | CHRM4 (0.58) | BRD4HSD11B1CHRM4ALDH1A1GAA | |
| SCHEMBL8922008 | 0.82 | CHRM4 (0.59) | BRD4HSD11B1MEN1KMT2ACHRM4 | |
| SCHEMBL14379106 | 0.82 | L3MBTL1 (0.67) | BRD4HSD11B1MEN1KMT2ACHRM4 | |
| SCHEMBL4035554 | 0.80 | SMN1; SMN2 (0.72) | MEN1KMT2ACHRM4ALDH1A1SMN1; SMN2 | |
| SCHEMBL11437380 | 0.80 | MEN1 (0.50) | BRD4MEN1KMT2ACHRM4ALDH1A1 | |
| SCHEMBL28351668 | 0.80 | PRMT5 (0.60) | BRD4KMT2ACHRM4ALDH1A1GAA | |
| SCHEMBL31073550 | 0.79 | KCNH2 (0.56) | BRD4HSD11B1MEN1KMT2ACHRM4 | |
| SCHEMBL4392358 | 0.79 | PRMT5 (0.56) | HSD11B1ALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL5451965 | 0.79 | CHRM4 (0.55) | BRD4HSD11B1CHRM4ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |