Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 11/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446527 | 0.91 | CNR1 (0.47) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5446388 | 0.89 | CNR2 (0.51) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL14464374 | 0.88 | CHRNB2 (0.41) | ALDH1A1MAPTNPSR1CNR1CNR2 | |
| SCHEMBL5446352 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPTNPSR1CNR1CNR2 | |
| SCHEMBL5451547 | 0.85 | PDE10A (0.47) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5378744 | 0.85 | CNR2 (0.44) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5443022 | 0.84 | PRPS1 (0.45) | ALDH1A1CNR1CNR2KDM2BCHRNB2 | |
| SCHEMBL5454463 | 0.84 | TSHR (0.46) | MAPTNPSR1CNR1CNR2CHRNB2 | |
| SCHEMBL14464377 | 0.83 | CHRNB2 (0.42) | CNR1CNR2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5448730 | 0.82 | CNR1 (0.42) | ALDH1A1CNR1CNR2CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | GIPR, GHSR, GHRHR | ALDH1A1 2963/4885MAPT 4523/4885NPSR1 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.