Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415787 | 0.68 | LMNA (0.45) | RAB9AALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL5459533 | 0.66 | KMT2A (0.80) | ALDH1A1KDM4EKMT2ASMN1; SMN2MAPT | |
| SCHEMBL2680169 | 0.66 | ALDH1A1 (0.66) | NPC1RAB9AEPHX1ALDH1A1GAA | |
| Ethylene SCHEMBL28911980 | 0.65 | EPHX1 (0.69) | NPC1RAB9AEPHX1ALDH1A1GAA | |
| SCHEMBL9616703 | 0.65 | LOX (0.41) | RAB9AALDH1A1GAAKMT2AMAPK1 | |
| SCHEMBL5161443 | 0.65 | NPC1 (0.87) | NPC1RAB9AEPHX1ALDH1A1GAA | |
| SCHEMBL2784650 | 0.63 | LMNA (0.40) | RAB9AALDH1A1GAAKMT2AMAPK1 | |
| SCHEMBL9616973 | 0.63 | LOX (0.39) | RAB9AALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL16587379 | 0.63 | NPC1 (0.77) | NPC1RAB9AEPHX1ALDH1A1GAA | |
| SCHEMBL8217266 | 0.62 | LOX (0.36) | RAB9AALDH1A1GAAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |