Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NAPEPLD | Q6IQ20 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462475 | 0.92 | KDM4E (0.40) | HCRTR1HCRTR2LMNASMN1; SMN2KDM4E | |
| SCHEMBL5450960 | 0.79 | HRH4 (0.42) | SMN1; SMN2KDM4EALDH1A1HTTMCHR1 | |
| SCHEMBL5452783 | 0.77 | NUDT1 (0.51) | LMNASMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL5444088 | 0.74 | CRHR1 (0.37) | HCRTR1HCRTR2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5448462 | 0.73 | TSHR (0.37) | P2RY12HCRTR1HCRTR2LMNASMN1; SMN2 | |
| SCHEMBL5452827 | 0.73 | NUDT1 (0.47) | LMNASMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL16896324 | 0.70 | IKBKB (0.35) | P2RY12LMNASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL18243919 | 0.70 | IKBKB (0.35) | P2RY12LMNASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL27680972 | 0.69 | RBP4 (0.54) | KDM4EHSD17B10USP2HPGDNPSR1 | |
| SCHEMBL27379669 | 0.65 | METAP2 (0.37) | PDE10AMCHR1METAP2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ARAF, BRAF, RAF1 | P2RY12 2370/4885HCRTR1 4474/4885HCRTR2 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.