Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445865 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1GAATSHR | |
| SCHEMBL5449642 | 0.86 | RAB9A (0.60) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL5446625 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL5455033 | 0.83 | NPC1 (0.60) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL5456707 | 0.82 | MEN1 (0.51) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL5451777 | 0.81 | ALDH1A1 (0.60) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL14096064 | 0.76 | GAA (0.53) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL14096058 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL5455082 | 0.74 | ALDH1A1 (0.53) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL28945218 | 0.74 | EPHX1 (0.73) | RAB9ANPC1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |