Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449642 | 0.86 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL5446625 | 0.86 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL5445865 | 0.84 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL5451777 | 0.84 | ALDH1A1 (0.60) | NPC1RAB9ASMN1; SMN2GAAPOLB | |
| SCHEMBL5453400 | 0.83 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2GAAPKM | |
| SCHEMBL14096064 | 0.79 | GAA (0.53) | NPC1RAB9ASMN1; SMN2GAAPOLB | |
| SCHEMBL14096058 | 0.78 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL16358841 | 0.74 | KMT2A (0.70) | NPC1RAB9ASMN1; SMN2PKMPOLB | |
| SCHEMBL5450048 | 0.74 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2GAAPOLB | |
| SCHEMBL5448122 | 0.74 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |