Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453400 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL5455033 | 0.84 | NPC1 (0.60) | SMN1; SMN2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL5446625 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL5449642 | 0.84 | RAB9A (0.60) | SMN1; SMN2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL5452802 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL5451777 | 0.82 | ALDH1A1 (0.60) | SMN1; SMN2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL5445679 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL12067341 | 0.79 | SIRT1 (0.71) | SMN1; SMN2ALDH1A1MAPTLMNASIRT1 | |
| SCHEMBL14096064 | 0.77 | GAA (0.53) | SMN1; SMN2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL16677197 | 0.77 | MIF (0.66) | SMN1; SMN2ALDH1A1MAPTLMNASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |