Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 2/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | FLT3 | P36888 | 2/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459967 | 0.85 | MAPT (0.59) | RAB9AKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5465623 | 0.81 | RAB9A (0.60) | RAB9AMAPTSMN1; SMN2AURKAKDR | |
| SCHEMBL5463529 | 0.80 | KMT2A (0.62) | RAB9AKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL6282915 | 0.76 | RAB9A (0.74) | RAB9AKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL13853439 | 0.76 | MAPT (0.51) | RAB9AKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL6285776 | 0.76 | RAB9A (0.74) | RAB9AKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL12539734 | 0.75 | CCNT1 (0.53) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL5459405 | 0.74 | RAB9A (0.62) | RAB9AKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5464860 | 0.74 | MAPKAPK2 (0.48) | RAB9AMAPTSMN1; SMN2FLT3P2RY1 | |
| SCHEMBL5458464 | 0.74 | MAPT (0.56) | RAB9AKMT2AMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | RAB9A 1528/4885KMT2A 1350/4885MAPT 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.