Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | WEE1 | P30291 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CDK7 | P50613 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460991 | 0.85 | RAB9A (0.59) | RAB9APOLBSMN1; SMN2SLC27A1WEE1 | |
| SCHEMBL5459265 | 0.84 | RAB9A (0.53) | RAB9APOLBSMN1; SMN2SLC27A1MTOR | |
| SCHEMBL5453617 | 0.81 | RAB9A (0.60) | RAB9ASMN1; SMN2PIK3CAMTORPDE7A | |
| SCHEMBL5466915 | 0.80 | SMN1; SMN2 (0.56) | RAB9APOLBSMN1; SMN2SLC27A1MTOR | |
| SCHEMBL5459405 | 0.76 | RAB9A (0.62) | RAB9APOLBSMN1; SMN2PIK3CAMTOR | |
| SCHEMBL5464860 | 0.76 | MAPKAPK2 (0.48) | RAB9APOLBSMN1; SMN2PIK3CAMTOR | |
| SCHEMBL13853439 | 0.76 | MAPT (0.51) | RAB9ASMN1; SMN2PIK3CAMTORNPC1 | |
| SCHEMBL5462600 | 0.74 | PIK3CA (0.49) | RAB9ASMN1; SMN2PIK3CAMTORFLT3 | |
| SCHEMBL5458305 | 0.74 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2PIK3CAMTORNPC1 | |
| SCHEMBL5458464 | 0.74 | MAPT (0.56) | RAB9APOLBNPC1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | RAB9A 1528/4885POLB 4280/4885SMN1; SMN2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.