Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448762 | 0.89 | SMN1; SMN2 (0.56) | CNR1SMN1; SMN2CNR2POLBALDH1A1 | |
| SCHEMBL5449197 | 0.88 | NR4A2 (0.57) | NR4A2CNR1L3MBTL1TSHRGAA | |
| SCHEMBL5457612 | 0.88 | CNR2 (0.46) | CNR1SMN1; SMN2MAPTCNR2NPSR1 | |
| SCHEMBL5456168 | 0.84 | L3MBTL1 (0.61) | NR4A2CNR1L3MBTL1TSHRGAA | |
| SCHEMBL5451287 | 0.82 | L3MBTL1 (0.54) | NR4A2CNR1L3MBTL1TSHRGAA | |
| SCHEMBL5456428 | 0.82 | GAA (0.56) | NR4A2CNR1L3MBTL1TSHRGAA | |
| SCHEMBL5450991 | 0.82 | NR4A2 (0.60) | NR4A2CNR1L3MBTL1TSHRGAA | |
| SCHEMBL5452278 | 0.82 | CNR1 (0.59) | NR4A2CNR1L3MBTL1TSHRGAA | |
| SCHEMBL5446521 | 0.79 | HTR1A (0.55) | NR4A2CNR1L3MBTL1TSHRGAA | |
| Hydrochloric Acid SCHEMBL5444470 | 0.78 | ADRA1D (0.60) | NR4A2CNR1L3MBTL1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | GIPR, GHSR, GHRHR | NR4A2 265/4885CNR1 65/4885L3MBTL1 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.