Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758273 | 0.79 | CNR1 (0.39) | ALDH1A1MAPK1CNR1KMT2AMEN1 | |
| SCHEMBL3027638 | 0.73 | GAA (0.59) | CYP19A1TRPC5TDP1ALDH1A1CYP2C19 | |
| SCHEMBL4758299 | 0.72 | LMNA (0.42) | TDP1ALDH1A1CYP2C19TSHRKMT2A | |
| SCHEMBL4755336 | 0.66 | LMNA (0.42) | ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL14710358 | 0.66 | OPRM1 (0.53) | CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23580189 | 0.65 | ELANE (0.54) | CYP19A1TRPC5ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL11451541 | 0.65 | GAA (0.53) | ALDH1A1CYP2C19TSHRHPGDCYP3A4 | |
| SCHEMBL4758575 | 0.64 | OPRM1 (0.39) | TSHR | |
| SCHEMBL4757277 | 0.64 | TSHR (0.34) | ALDH1A1TSHRLMNA | |
| SCHEMBL4746788 | 0.62 | ALDH1A1 (0.60) | TRPC5ALDH1A1MAPK1CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | CYP19A1 2563/4885TRPC5 1050/4885TDP1 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.