Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458309 | 0.87 | ME2 (0.56) | GFERALDH1A1KMT2ATMEM97SIGMAR1 | |
| SCHEMBL5468405 | 0.87 | KDM4E (0.67) | MAPTALDH1A1KMT2ATMEM97SIGMAR1 | |
| SCHEMBL5467837 | 0.86 | PANK3 (0.49) | GFERMAPTL3MBTL1ALDH1A1TSHR | |
| SCHEMBL5461558 | 0.85 | KDM4E (0.58) | MAPTL3MBTL1ALDH1A1TSHRKMT2A | |
| SCHEMBL5453428 | 0.85 | KDM4E (0.52) | ALDH1A1KMT2ATMEM97SIGMAR1CHRM4 | |
| SCHEMBL5464941 | 0.85 | ME2 (0.58) | ALDH1A1KMT2ASMN1; SMN2TMEM97SIGMAR1 | |
| SCHEMBL5455992 | 0.85 | HRH3 (0.53) | ALDH1A1TMEM97SIGMAR1CHRM4HTR1A | |
| SCHEMBL5459927 | 0.82 | SIGMAR1 (0.49) | ALDH1A1TMEM97SIGMAR1CHRM4HTR1A | |
| SCHEMBL5460606 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL5459210 | 0.81 | MAPT (0.57) | GFERMAPTKMT2ASMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | GFER 1969/4885MAPT 1504/4885L3MBTL1 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.