Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 1/20 | 0.56 |
| ▸ | ME1 | P48163 | 1/20 | 0.56 |
| ▸ | ME3 | Q16798 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HRH2 | P25021 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468405 | 0.90 | KDM4E (0.67) | ME2ME1ME3MEN1KMT2A | |
| SCHEMBL5467837 | 0.89 | PANK3 (0.49) | ME2ME1ME3MEN1KMT2A | |
| SCHEMBL5453428 | 0.88 | KDM4E (0.52) | ME2ME1ME3MEN1KMT2A | |
| SCHEMBL5454869 | 0.87 | GFER (0.58) | KMT2AGFERKDM4EALDH1A1HRH3 | |
| SCHEMBL5464941 | 0.87 | ME2 (0.58) | ME2ME1ME3MEN1KMT2A | |
| SCHEMBL5455992 | 0.85 | HRH3 (0.53) | ME2ME1ME3KDM4EALDH1A1 | |
| SCHEMBL5472454 | 0.84 | HRH3 (0.64) | KMT2AKDM4EALDH1A1HRH3TMEM97 | |
| SCHEMBL5459927 | 0.84 | SIGMAR1 (0.49) | KDM4EALDH1A1HRH3TMEM97SIGMAR1 | |
| SCHEMBL5460606 | 0.84 | ALDH1A1 (0.53) | MEN1KMT2AKDM4EALDH1A1HRH3 | |
| SCHEMBL5463790 | 0.81 | TMEM97 (0.45) | KDM4EALDH1A1HRH3TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | ME2 720/4885ME1 1776/4885ME3 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.