Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5472454 | 0.89 | HRH3 (0.64) | L3MBTL1ALDH1A1KDM4EL3MBTL3KMT2A | |
| SCHEMBL5465885 | 0.88 | KDM4E (0.60) | L3MBTL1ALDH1A1KDM4EHTTL3MBTL3 | |
| SCHEMBL5464902 | 0.87 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1KDM4EHTTL3MBTL3 | |
| SCHEMBL5459749 | 0.85 | KDM2B (0.55) | L3MBTL1ALDH1A1KDM4EL3MBTL3MEN1 | |
| SCHEMBL5459697 | 0.84 | L3MBTL3 (0.57) | L3MBTL1ALDH1A1KDM4EL3MBTL3HRH3 | |
| SCHEMBL5465825 | 0.84 | LMNA (0.58) | L3MBTL1ALDH1A1KDM4EHTTL3MBTL3 | |
| SCHEMBL5466155 | 0.84 | PKM (0.55) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5464881 | 0.83 | KDM4E (0.60) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2L3MBTL3 | |
| SCHEMBL5466062 | 0.83 | HSD11B1 (0.50) | L3MBTL1ALDH1A1KDM4EHTTL3MBTL3 | |
| SCHEMBL5468207 | 0.82 | POLB (0.56) | L3MBTL1ALDH1A1KDM4EL3MBTL3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185089-A1 | Benzazepine derivatives for the treatment of neurological and psychiatric disorders | CNR2, GRIN2C, GRIN2B | L3MBTL1 3089/4885ALDH1A1 1805/4885KDM4E 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.