Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460864 | 0.88 | WNT3A (0.54) | DGAT1SMN1; SMN2LMNAKDM4EMAPK1 | |
| SCHEMBL5466996 | 0.87 | DGAT1 (0.55) | DGAT1SMN1; SMN2LMNAKDM4EMAPK1 | |
| SCHEMBL5460071 | 0.86 | KMT2A (0.59) | SMN1; SMN2LMNAKDM4EMAPK1HTT | |
| SCHEMBL5459635 | 0.84 | MAPK1 (0.51) | DGAT1SMN1; SMN2LMNAKDM4EMAPK1 | |
| SCHEMBL5455802 | 0.84 | KMT2A (0.59) | SMN1; SMN2LMNAKDM4EHSD17B10P2RY12 | |
| SCHEMBL5465441 | 0.81 | MAPT (0.49) | DGAT1SMN1; SMN2LMNAKDM4EP2RY12 | |
| SCHEMBL5456953 | 0.81 | MAPT (0.51) | DGAT1SMN1; SMN2LMNAKDM4EMAPK1 | |
| SCHEMBL2829336 | 0.80 | SMN1; SMN2 (0.57) | DGAT1SMN1; SMN2LMNAKDM4EMAPK1 | |
| SCHEMBL5460956 | 0.80 | LMNA (0.50) | SMN1; SMN2LMNAKDM4EMAPK1HTT | |
| SCHEMBL5464835 | 0.78 | MAPT (0.53) | SMN1; SMN2LMNAHTTHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | DGAT1 3/4885SMN1; SMN2 4424/4885LMNA 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.