Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
| ▸ | JAK2 | O60674 | 6/20 | 0.53 |
| ▸ | JAK3 | P52333 | 6/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459789 | 0.87 | NAMPT (0.56) | NAMPTJAK2JAK3PTK2RAB9A | |
| SCHEMBL5458069 | 0.87 | NAMPT (0.65) | NAMPTJAK2JAK3PTK2RAB9A | |
| SCHEMBL5458362 | 0.86 | RAB9A (0.58) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL5466754 | 0.85 | NAMPT (0.61) | NAMPTJAK2JAK3PTK2RAB9A | |
| SCHEMBL5460804 | 0.84 | MAPT (0.68) | NAMPTRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL7667693 | 0.82 | NAMPT (0.69) | NAMPTJAK2JAK3PTK2RAB9A | |
| SCHEMBL1989165 | 0.81 | NAMPT (0.65) | NAMPTJAK3RAB9ANPC1MAPT | |
| SCHEMBL1989164 | 0.81 | NAMPT (0.65) | NAMPTJAK3RAB9ANPC1MAPT | |
| SCHEMBL16835041 | 0.81 | NAMPT (0.67) | NAMPTJAK2JAK3PTK2RAB9A | |
| SCHEMBL10127488 | 0.79 | NAMPT (0.71) | NAMPTJAK2JAK3PTK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | NAMPT 324/4885JAK2 3780/4885JAK3 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.