Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.67 |
| ▸ | CTSK | P43235 | 5/20 | 0.67 |
| ▸ | CTSC | P53634 | 3/20 | 0.64 |
| ▸ | CTSL | P07711 | 8/20 | 0.59 |
| ▸ | CTSB | P07858 | 5/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924660 | 1.00 | CTSS (0.67) | CTSSCTSKCTSCCTSLCTSB | |
| SCHEMBL16626138 | 1.00 | CTSS (0.67) | CTSSCTSKCTSCCTSLCTSB | |
| SCHEMBL6019626 | 0.88 | CTSL (0.59) | CTSSCTSKCTSCCTSLSLC7A5 | |
| SCHEMBL6020765 | 0.86 | CTSC (0.59) | CTSSCTSKCTSCALPIPKM | |
| SCHEMBL583171 | 0.85 | ALPI (0.58) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL583172 | 0.85 | ALPI (0.58) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL6019536 | 0.84 | CTSS (0.61) | CTSSCTSKCTSCCTSLCTSB | |
| SCHEMBL10001637 | 0.84 | CTSC (0.56) | CTSSCTSKCTSCALPIPKM | |
| SCHEMBL988104 | 0.83 | ALPI (0.59) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL6653906 | 0.83 | ALPI (0.59) | CTSCALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099958-A1 | Protease inhibitors | PROZYMEX A/S (DK) | 2007-05-03 | — | — | US | claimed |
| US-20070099958-A1 | Protease inhibitors | PROZYMEX A/S (DK) | 2007-05-03 | — | — | US | disclosed |
| US-20070099958-A1 | Protease inhibitors | PROZYMEX A/S (DK) | 2007-05-03 | — | — | US | disclosed |
| US-20070099958-A1 | Protease inhibitors | PROZYMEX A/S (DK) | 2007-05-03 | — | — | US | disclosed |
| US-20060122184-A1 | Cyanomethyl derivatives as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | disclosed |
| EP-1638925-A1 | PROTEASE INHIBITORS | Prozymex A/S (DK) | 2006-03-29 | — | — | EP | disclosed |
| EP-1569954-A1 | CYANOMETHYL DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004110988-A1 | PROTEASE INHIBITORS | PROZYMEX A/S (DK) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004110988-A1 | PROTEASE INHIBITORS | PROZYMEX A/S (DK) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004052921-A1 | CYANOMETHYL DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099958-A1 | Protease inhibitors | CTSC, DPP7, BACE1 | CTSS 10/4885CTSK 5/4885CTSC 1/4885 |
| US-20060122184-A1 | Cyanomethyl derivatives as cysteine protease inhibitors | CTSF, CTSB, CTSK | CTSS 4/4885CTSK 3/4885CTSC 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.