Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14859717 | 0.89 | KMT2A (0.66) | RAB9AKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL14859669 | 0.87 | ALDH1A1 (0.63) | RAB9AALDH1A1NPC1LMNAPOLB | |
| SCHEMBL14860407 | 0.86 | RAB9A (1.00) | RAB9AKDM4EALDH1A1MITFNPC1 | |
| SCHEMBL5444784 | 0.85 | RAB9A (0.66) | RAB9AALDH1A1NPC1LMNAPOLB | |
| SCHEMBL166484 | 0.85 | LMNA (0.82) | RAB9AKDM4EALDH1A1NPC1LMNA | |
| Hydrochloric Acid SCHEMBL27843329 | 0.83 | LMNA (0.80) | RAB9AKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL9859901 | 0.81 | SMN1; SMN2 (0.67) | RAB9AALDH1A1NPC1LMNANPSR1 | |
| SCHEMBL4030184 | 0.80 | RAB9A (0.63) | RAB9AKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL1743418 | 0.79 | SMN1; SMN2 (0.59) | RAB9AKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL14096444 | 0.79 | ALDH1A1 (1.00) | KDM4EALDH1A1MITFNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814366-B2 | Antiviral compounds and use thereof | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2023-11-14 | — | — | US | disclosed |
| US-20210070737-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | UNIVERSITA DEGLE STUDI DI SIENA (IT) | 2021-03-11 | — | — | US | disclosed |
| EP-3765454-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | Universita' Degli Studi di Siena (IT) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019175436-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2019-09-19 | — | — | WO | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814366-B2 | Antiviral compounds and use thereof | MAVS, EIF2AK2, SARS1 | RAB9A 1894/4885KDM4E 2361/4885ALDH1A1 2154/4885 |
| US-20210070737-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MAVS, EIF2AK2, SARS1 | RAB9A 1894/4885KDM4E 2361/4885ALDH1A1 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.