Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 13/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972804 | 0.72 | HTR7 (0.43) | HTR7HTR1AHTR2ADRD2 | |
| SCHEMBL14363101 | 0.69 | SERPINE1 (0.45) | HTR7HTR1AHTR2ADRD2SLC6A4 | |
| SCHEMBL10531206 | 0.68 | SLC6A4 (0.50) | HTR7HTR1AHTR2ADRD2SLC6A4 | |
| SCHEMBL8624418 | 0.65 | SERPINE1 (0.54) | HTR7HTR1AHTR2ADRD2SERPINE1 | |
| SCHEMBL12574466 | 0.63 | HTR7 (0.46) | HTR7HTR1AHTR2ADRD2SERPINE1 | |
| SCHEMBL10534853 | 0.63 | HTR7 (0.42) | HTR7HTR1AHTR2ADRD2SLC6A4 | |
| SCHEMBL8588324 | 0.63 | SLC6A4 (0.58) | HTR7HTR1AHTR2ADRD2SLC6A4 | |
| SCHEMBL5174350 | 0.63 | ALDH1A1 (0.61) | HTR7HTR1AHTR2ADRD2SLC6A4 | |
| SCHEMBL2666854 | 0.62 | CDK2 (0.46) | HTR7HTR1AHTR2ADRD2SLC6A4 | |
| SCHEMBL12693414 | 0.61 | SLC6A4 (0.56) | HTR7HTR1AHTR2ADRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | HTR7 2124/4885HTR1A 484/4885HTR2A 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.