⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3596041 | 0.88 | KMT2A (0.33) | — | |
| SCHEMBL6839514 | 0.85 | FPR2 (0.32) | — | |
| SCHEMBL5464784 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL1475659 | 0.81 | ALDH1A1 (0.33) | — | |
| SCHEMBL5446723 | 0.79 | — | — | |
| SCHEMBL7780291 | 0.79 | CRBN (0.33) | — | |
| SCHEMBL5437164 | 0.78 | KMT2A (0.38) | — | |
| SCHEMBL3169698 | 0.78 | — | — | |
| SCHEMBL2426125 | 0.77 | ADAM17 (0.30) | — | |
| SCHEMBL5929376 | 0.77 | L3MBTL1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225170-A1 | 2-Halo-6-Alkylphenyl-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
| EP-1682501-A2 | 2-HALOGEN-6-ALKYL-PHENYL SUBSTITUTED TETRAMIC ACID DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044791-A2 | 2-HALOGEN-6-ALKYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | WO | disclosed |