Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889210 | 0.88 | KMT2A (0.41) | KMT2APDE7APOLBNPC1RAB9A | |
| SCHEMBL5435809 | 0.85 | BACE1 (0.32) | — | |
| SCHEMBL3001186 | 0.83 | KMT2A (0.36) | KMT2APDE7AALDH1A1 | |
| SCHEMBL5107358 | 0.83 | KMT2A (0.35) | KMT2APDE7ANPC1RAB9A | |
| SCHEMBL8652013 | 0.79 | KMT2A (0.40) | KMT2APDE7APOLBNPC1RAB9A | |
| SCHEMBL5464784 | 0.79 | ALDH1A1 (0.31) | ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL3077698 | 0.79 | THRB (0.37) | KMT2APDE7AALDH1A1KDM4E | |
| SCHEMBL5458693 | 0.78 | — | — | |
| SCHEMBL8645554 | 0.77 | KMT2A (0.38) | KMT2APDE7APOLBALDH1A1NPC1 | |
| SCHEMBL1475886 | 0.77 | KMT2A (0.37) | KMT2APDE7APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1697321-A1 | 2-HALOGEN-6-ALKYL-PHENYL SUBSTITUTED SPIROCYCLIC TETRAMIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005044796-A1 | 2-HALOGEN-6-ALKYL-PHENYL SUBSTITUTED SPIROCYCLIC TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | TBCA, CA6, TRIP13 | KMT2A 2816/4885PDE7A 2859/4885POLB 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.