Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605762 | 0.87 | ALDH1A1 (0.39) | HSD17B1HSD17B2ALDH1A1ALOX15CES2 | |
| SCHEMBL5272363 | 0.87 | ALDH1A1 (0.39) | HSD17B1HSD17B2ALDH1A1ALOX15MEN1 | |
| SCHEMBL10912845 | 0.86 | HSD17B1 (0.40) | HSD17B1HSD17B2ALDH1A1ALOX15KDM4E | |
| SCHEMBL1617264 | 0.83 | HSD17B10 (0.49) | HSD17B1HSD17B2ALDH1A1CDK1CDK4 | |
| SCHEMBL18186528 | 0.82 | HSD17B1 (0.38) | HSD17B1HSD17B2ALDH1A1ALOX15CES2 | |
| SCHEMBL28113807 | 0.80 | HSD17B1 (0.43) | HSD17B1HSD17B2ALDH1A1ALOX15TUBB1 | |
| SCHEMBL28746145 | 0.79 | HSD17B1 (0.32) | HSD17B1HSD17B2 | |
| SCHEMBL27930766 | 0.78 | CES2 (0.44) | HSD17B1HSD17B2ALDH1A1ALOX15CES2 | |
| SCHEMBL345016 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ALOX15CES2CES1POLB | |
| SCHEMBL21946023 | 0.76 | ALDH1A1 (0.37) | HSD17B1HSD17B2ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377826-B | Green synthesis process of key intermediate of quinolone | 浙江本立科技股份有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-111377826-A | Green synthesis process of key intermediate of quinolone | 浙江本立科技股份有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
| EP-1343766-B1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | PROCTER & GAMBLE (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1343766-A1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048113-A1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
| US-6207678-B1 | USED FOR TREATING INFLAMMATORY DISEASE SUCH AS ARTHRITIS, PSORIASIS, ASTHMA OR INFLAMMATORY BOWEL DISEASE, CENTRAL NERVOUS SYSTEM DISORDER SUCH AS ANXIETY, DEPRESSION, DEMENTIA OR PSYCHOSIS, GASTROINTESTINAL DISORDERS | PFIZER INC | 2001-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | HSD17B1 881/4885HSD17B2 679/4885ALDH1A1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.