Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607945 | 0.85 | HSD17B10 (0.44) | HSD17B10KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL6422815 | 0.85 | HSD17B10 (0.44) | HSD17B10KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL5458697 | 0.83 | HSD17B1 (0.39) | HSD17B10MEN1KMT2AKDM4ELMNA | |
| SCHEMBL27927680 | 0.83 | HSD17B10 (0.43) | HSD17B10KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL27540803 | 0.82 | HSD17B10 (0.50) | HSD17B10KEAP1NFE2L2KDM4ETDP1 | |
| SCHEMBL28603127 | 0.82 | KEAP1 (0.48) | HSD17B10KEAP1NFE2L2KDM4ELMNA | |
| SCHEMBL18186481 | 0.81 | HSD17B10 (0.42) | HSD17B10KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL7182462 | 0.81 | KDM4E (0.45) | HSD17B10KEAP1NFE2L2KDM4ETDP1 | |
| SCHEMBL28937179 | 0.81 | HSD17B10 (0.39) | HSD17B10KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL28424948 | 0.81 | HSD17B10 (0.44) | HSD17B10KEAP1NFE2L2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844533-B | Amino-propanediol class compound, preparation method and its medical usage containing five yuan of heteroaromatics | 中国医学科学院药物研究所 | 2019-04-09 | — | — | CN | disclosed |
| CN-103705519-B | Cyclic triazo and diazo sodium channel blockers | 格林威治大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-104844533-A | Five-membered aromatic heterocycle-containing amino propanediol compounds, preparation method, and medical uses thereof, | INST MATERIA MEDICA CAMS | 2015-08-19 | — | — | CN | disclosed |
| US-9102665-B2 | Cysteinyl leukotriene antagonists | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2015-08-11 | — | — | US | disclosed |
| CN-104739839-A | NEW MEDICAL USE OF TRIAZINE DERIVATIVES | UNIV GREENWICH | 2015-07-01 | — | — | CN | disclosed |
| CN-104302623-A | Piperidine compound and pest-control use therefore | SUMITOMO CHEMICAL CO | 2015-01-21 | — | — | CN | disclosed |
| CN-101316853-B | Benzothiazole and thiazolopyridine as SIRTUIN modulators | SIRTRIS PHARMACEUTICALS INC | 2014-09-24 | — | — | CN | disclosed |
| US-8754107-B2 | Aminopyrrolidines as chemokine receptor antagonists | ABBVIE INC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20140155596-A1 | CYSTEINYL LEUKOTRIENE ANTAGONISTS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2014-06-05 | — | — | US | disclosed |
| CN-103705519-A | Cyclic triazo and diazo sodium channel blockers | UNIV GREENWICH | 2014-04-09 | — | — | CN | disclosed |
| CN-1802091-A | Use of isoindolinone derivatives as insecticides | BAYER CROPSCIENCE AG (DE) | 2006-07-12 | — | — | CN | disclosed |
| CN-1768054-A | Novel cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors | AVENTIS PHARMA SA (FR) | 2006-05-03 | — | — | CN | disclosed |
| CN-1668576-A | Tetrafluorobenzyl derivatives and pharmaceutical composition for treating and preventing acute and chronic neurodegenerative diseases of central nervous system containing the same | NEUROTECH CO LTD (KR) | 2005-09-14 | — | — | CN | disclosed |
| CN-1302799-A | Sulfonium salt compound | WAKO PURE CHEM IND LTD (JP) | 2001-07-11 | — | — | CN | disclosed |
| EP-0741122-B1 | Process for preparing aromatic compounds through decarboxylation of aromatic carboxylic acids | CLARIANT GMBH (DE) | 1999-08-25 | — | — | EP | disclosed |
| US-5739388-A | Process for the preparation of aromatic compounds by decarboxylation of aromatic carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0667334-B1 | Process for the preparation of 4-alkoxy-3,5,6-trifluorophthalic acids and 3-alkoxy-2,4,5-trifluorobenzoic acids | CLARIANT GMBH (DE) | 1998-01-07 | — | — | EP | disclosed |
| EP-0741122-A1 | Process for preparing aromatic compounds through decarboxylation of aromatic carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-06 | — | — | EP | disclosed |
| US-5488152-A | Process for the preparation of 4-alkoxy-3,5,6-trifluoro-phthalic acids and 3-alkoxy-2,4,5-trifluorobenzoic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-30 | — | — | US | disclosed |
| EP-0667334-A2 | Process for the preparation of 4-alkoxy-3,5,6-trifluorophthalic acids and 3-alkoxy-2,4,5-trifluorobenzoic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155596-A1 | CYSTEINYL LEUKOTRIENE ANTAGONISTS | LTC4S, CYSLTR2, CYSLTR1 | HSD17B10 1737/4885KEAP1 109/4885NFE2L2 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.