Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 5/20 | 0.32 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.32 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.32 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467747 | 0.87 | FLT1 (0.31) | — | |
| SCHEMBL5457246 | 0.83 | NR3C1 (0.32) | — | |
| SCHEMBL5458893 | 0.81 | NTRK1 (0.31) | — | |
| SCHEMBL5458940 | 0.72 | NR3C1 (0.33) | — | |
| SCHEMBL5458870 | 0.71 | — | — | |
| SCHEMBL5471627 | 0.69 | NR3C1 (0.35) | — | |
| SCHEMBL5460516 | 0.69 | NR3C1 (0.43) | — | |
| SCHEMBL5459844 | 0.69 | NR3C1 (0.34) | — | |
| SCHEMBL3535770 | 0.66 | BRD4 (0.31) | — | |
| SCHEMBL5467910 | 0.65 | NR3C1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015750-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAEURLE STEFAN | 2007-01-18 | — | — | US | disclosed |
| WO-2006108714-A2 | TETRAHYDRONAPHTHALENE DERIVATIVES METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF ANTIPHLOGISTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015750-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | DHPS, TNF, PTGES | EED 3823/4885SUZ12 3610/4885EZH2 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.