SCHEMBL5458919

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL256578	0.83	CTSL (0.64)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL2063876	0.83	CTSV (0.64)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL2063188	0.82	CTSV (0.60)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL7823652	0.79	CTSV (0.56)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL187798	0.79	CTSV (0.56)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL248836	0.79	CTSV (0.59)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL17067000	0.79	CTSV (0.58)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL18474478	0.78	CTSV (0.57)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL15730198	0.78	CTSV (0.57)	CTSLCTSVPOLBALDH1A1HPGD
	SCHEMBL18975225	0.78	SRD5A1 (0.60)	CTSLCTSVPOLBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.