Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758585 | 0.77 | FPR2 (0.37) | MAPTSMN1; SMN2ALDH1A1POLBFPR2 | |
| SCHEMBL5452071 | 0.75 | ABCC1 (0.43) | MAPTALDH1A1NPSR1CYP1A2CYP2C19 | |
| SCHEMBL3032095 | 0.69 | MTOR (0.53) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL719657 | 0.68 | DGAT1 (0.54) | ALOX5PTGESSMN1; SMN2ALDH1A1GABRA1 | |
| SCHEMBL4757298 | 0.68 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1FPR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31426389 | 0.67 | DGAT1 (0.53) | ALOX5PTGESSMN1; SMN2ALDH1A1GABRA1 | |
| SCHEMBL3030379 | 0.67 | MTOR (0.53) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL961701 | 0.65 | ALDH1A1 (0.52) | ALOX5PTGESSMN1; SMN2ALDH1A1GABRA1 | |
| SCHEMBL12185589 | 0.65 | OPRM1 (0.41) | MAPTALOX5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4089582 | 0.64 | KMT2A (0.39) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191409-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | MAPT 19/4885ALOX5 3023/4885PTGES 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.