Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | CPS1 | P31327 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | CLK3 | P49761 | 2/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | MAP3K19 | Q56UN5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758337 | 0.72 | HSD11B1 (0.36) | TSHR | |
| SCHEMBL31195695 | 0.72 | ELANE (0.40) | KMT2AKDM4EALDH1A1TSHRRAB9A | |
| SCHEMBL4757355 | 0.70 | PYGM (0.39) | ALDH1A1HTTGAALMNA | |
| SCHEMBL11390110 | 0.70 | TDP1 (0.37) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL4757333 | 0.67 | OPRM1 (0.36) | KMT2AALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL4757340 | 0.67 | NOTUM (0.34) | L3MBTL1POLB | |
| SCHEMBL9831573 | 0.65 | PTGS2 (0.31) | ALDH1A1LMNA | |
| SCHEMBL19438820 | 0.65 | KMT2A (0.54) | KMT2AKDM4ECPS1CYP3A4 | |
| SCHEMBL5458967 | 0.64 | MAPT (0.39) | KMT2AKDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL1051747 | 0.63 | CPS1 (0.63) | KMT2AKDM4ECPS1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006580-A1 | OPTIONALLY CONDENSED DIHYDROPYRIDINE, DIHYDROPYRIMIDINE AND DIHYDROPYRANE DERIVATIVES ACTING AS LATE SODIUM CHANNEL BLOCKERS | CV THERAPEUTICS, INC. (US) | 2009-01-08 | — | — | WO | disclosed |