Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463544 | 0.87 | MLNR (0.47) | MAPTCYP3A4RECQLKMT2AALDH1A1 | |
| SCHEMBL5465687 | 0.85 | MAOA (0.39) | MAPTCYP3A4L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL5456600 | 0.83 | MEN1 (0.45) | MAPTKMT2AMEN1TSHRGAA | |
| SCHEMBL5450686 | 0.83 | MEN1 (0.45) | MAPTKMT2AMEN1TSHRGAA | |
| SCHEMBL5461655 | 0.80 | PTGS2 (0.50) | KMT2AMEN1GAAGABBR2GABBR1 | |
| SCHEMBL5465032 | 0.80 | TXNRD1 (0.44) | ALDH1A1CA2CA1RAB9ATP53 | |
| SCHEMBL5461659 | 0.80 | PTGS2 (0.50) | KMT2AMEN1GAAGABBR2GABBR1 | |
| SCHEMBL4116222 | 0.77 | GLRA3 (0.46) | CYP3A4KMT2AALDH1A1MEN1TSHR | |
| SCHEMBL5450665 | 0.76 | RIPK1 (0.41) | MAPTCYP3A4KMT2AALDH1A1MEN1 | |
| SCHEMBL5450671 | 0.74 | ESR2 (0.44) | MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004799-A1 | Novel compounds for the treatment of obesity | NOVO NORDISK A/S (DK) | 2007-01-04 | — | — | US | claimed |
| EP-1689707-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2006-08-16 | — | — | EP | claimed |
| WO-2005051900-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2005-06-09 | — | — | WO | claimed |
| US-20070004799-A1 | Novel compounds for the treatment of obesity | NOVO NORDISK A/S (DK) | 2007-01-04 | — | — | US | disclosed |
| US-20070004799-A1 | Novel compounds for the treatment of obesity | NOVO NORDISK A/S (DK) | 2007-01-04 | — | — | US | disclosed |
| US-20070004799-A1 | Novel compounds for the treatment of obesity | NOVO NORDISK A/S (DK) | 2007-01-04 | — | — | US | disclosed |
| EP-1689707-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005051900-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004799-A1 | Novel compounds for the treatment of obesity | GPR119, NR4A3, NR4A1 | MAPT 4875/4885PKM 4484/4885CYP3A4 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.