Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MB | P02144 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350456 | 0.88 | NAPRT (0.52) | POLBSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL29465785 | 0.84 | GAA (0.38) | POLBL3MBTL1SMN1; SMN2HTTMAPT | |
| SCHEMBL14340359 | 0.77 | POLB (0.37) | POLBL3MBTL1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL19707372 | 0.75 | MAPT (0.47) | POLBSMN1; SMN2MAPTALDH1A1TDP1 | |
| SCHEMBL25041715 | 0.73 | NR1H4 (0.51) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL4493409 | 0.73 | MAPT (0.47) | POLBL3MBTL1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL3374091 | 0.73 | POLB (0.58) | POLBSMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL14269954 | 0.73 | KIF11 (0.48) | POLBSMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL1646972 | 0.73 | NAPRT (0.46) | POLBSMN1; SMN2MAPTKMT2ATSHR | |
| SCHEMBL11245302 | 0.72 | L3MBTL1 (0.55) | POLBL3MBTL1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | Terpetschnig, Ewald (US) | 2007-12-06 | — | — | US | disclosed |
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | Terpetschnig, Ewald (US) | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | SPR, SRRT, SQLE | POLB 4726/4885L3MBTL1 2272/4885SMN1; SMN2 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.