Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 11/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946002 | 0.83 | MAPT (0.55) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL17034742 | 0.80 | SHMT2 (0.69) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL27367274 | 0.78 | GAA (0.55) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL4664731 | 0.77 | MAPT (0.70) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL4620529 | 0.77 | GAA (0.55) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL5454653 | 0.76 | MAPT (0.54) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL8015635 | 0.76 | MAPT (0.54) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL4350226 | 0.76 | KMT2A (0.45) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL8428059 | 0.74 | GAA (0.53) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL5462341 | 0.74 | MAPT (0.58) | MAPTMEN1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | MAPT 4163/4885MEN1 2892/4885KMT2A 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.