SCHEMBL546525

SCHEMBL546525

O=C(OCC12CC3CC(CC(CCl)(C3)C1)C2)C(C(F)(F)F)(C(F)(F)F)S(=O)(=O)OS(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546524 0.80
SCHEMBL15659577 0.80 SCN9A (0.38) KMT2AALDH1A1GAANPC1RAB9A
SCHEMBL17063683 0.80 SCN9A (0.38) KMT2AALDH1A1GAANPC1RAB9A
SCHEMBL961708 0.79 KMT2A (0.37) KMT2AALDH1A1GAANPC1RAB9A
SCHEMBL546894 0.76
SCHEMBL14778377 0.74 SCN9A (0.36) ALDH1A1GAANPC1RAB9A
SCHEMBL961481 0.72 ALDH1A1 (0.35) KMT2AALDH1A1GAANPC1RAB9A
SCHEMBL547384 0.70 MAPK1 (0.32) KMT2AGAASMN1; SMN2
SCHEMBL785676 0.69 SCN9A (0.35) KMT2AALDH1A1GAA
SCHEMBL515602 0.69 P2RX7 (0.37) KMT2AALDH1A1GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524440-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-09-03 US disclosed
US-8110336-B2 Resin and chemically amplified resist composition comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-07 US disclosed
US-20110165513-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY LTD (JP) 2011-07-07 US disclosed
US-20100075257-A1 Resin and Chemically Amplified Resist Composition Comprising the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-25 US disclosed