Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269272 | 0.87 | TSHR (0.48) | MAPK1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL5455930 | 0.81 | SMN1; SMN2 (0.54) | MAPK1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL11052562 | 0.81 | MAPT (0.61) | MAPK1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL5458467 | 0.80 | VCAM1 (0.49) | MAPK1ALDH1A1LMNAMAPTRAF1 | |
| SCHEMBL3819214 | 0.78 | HCAR3 (0.45) | MAPK1MAPTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL29392841 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL109574 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5471001 | 0.77 | AR (0.44) | MAPK1ALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL128166 | 0.77 | TSHR (0.45) | MAPK1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3819208 | 0.77 | ALDH1A1 (0.44) | MAPK1ALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | MAPK1 1466/4885ALDH1A1 731/4885LMNA 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.