Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.60 |
| ▸ | HTR2C | P28335 | 10/20 | 0.60 |
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812493 | 0.79 | HTR2A (0.57) | HTR2AHTR2CDRD2HTR6CHRNB2 | |
| SCHEMBL11806316 | 0.76 | HTR6 (0.57) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL7645002 | 0.75 | HTR2A (1.00) | HTR2AHTR2CDRD2HTR6 | |
| SCHEMBL5330477 | 0.75 | HTR2A (0.57) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL20970934 | 0.75 | HTR6 (0.71) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL29536604 | 0.75 | HTR6 (0.71) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL5330012 | 0.74 | HTR2A (0.49) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL30288461 | 0.74 | HTR2A (0.67) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL30288465 | 0.74 | HTR2A (0.67) | HTR2AHTR2CDRD2HTR6HTR1A | |
| SCHEMBL5308657 | 0.73 | HTR6 (0.46) | HTR2AHTR2CDRD2HTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |