Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.72 |
| ▸ | PLK1 | P53350 | 1/20 | 0.65 |
| ▸ | ABL1 | P00519 | 6/20 | 0.63 |
| ▸ | BCR | P11274 | 6/20 | 0.63 |
| ▸ | PRKCA | P17252 | 4/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.63 |
| ▸ | SRC | P12931 | 3/20 | 0.63 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | PRKCG | P05129 | 1/20 | 0.63 |
| ▸ | PRKCB | P05771 | 1/20 | 0.63 |
| ▸ | PRKCH | P24723 | 1/20 | 0.63 |
| ▸ | PRKCI | P41743 | 1/20 | 0.63 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.63 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.63 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.63 |
| ▸ | JAK3 | P52333 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5472892 | 0.87 | JAK2 (0.76) | JAK2JAK3POLBKMT2AMAPK8 | |
| SCHEMBL4733852 | 0.87 | PLK1 (0.84) | JAK2PLK1ABL1BCRPRKCA | |
| SCHEMBL4376512 | 0.84 | PLK1 (0.72) | JAK2PLK1ABL1BCRPRKCA | |
| SCHEMBL4378752 | 0.84 | JAK2 (1.00) | JAK2PLK1ABL1BCRPRKCA | |
| SCHEMBL5470852 | 0.84 | ADORA1 (0.69) | JAK2ABL1BCRPRKCAPDGFRB | |
| SCHEMBL5463021 | 0.82 | ABL1 (0.66) | JAK2PLK1ABL1PDGFRBPDGFRA | |
| SCHEMBL5462697 | 0.82 | ALDH1A1 (0.58) | JAK2ABL1BCRPRKCAPDGFRB | |
| SCHEMBL19706531 | 0.79 | NPC1 (0.71) | JAK2PLK1JAK3POLBKMT2A | |
| SCHEMBL5465350 | 0.79 | SIRT2 (0.68) | JAK2ABL1BCRPRKCAPDGFRB | |
| SCHEMBL4736493 | 0.79 | PLK1 (0.83) | JAK2PLK1ABL1BCRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | JAK2 2119/4885PLK1 3377/4885ABL1 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.