Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 7/20 | 0.76 |
| ▸ | JAK3 | P52333 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | PRNP | P04156 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | IKBKB | O14920 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466956 | 0.87 | JAK2 (0.72) | JAK2JAK3KMT2APOLBALDH1A1 | |
| SCHEMBL4378752 | 0.87 | JAK2 (1.00) | JAK2JAK3CAMK2DMAPK8 | |
| SCHEMBL5470852 | 0.87 | ADORA1 (0.69) | JAK2JAK3KDM4EMAPTRXFP1 | |
| SCHEMBL5473232 | 0.86 | DYRK1A (0.63) | JAK2JAK3MEN1KMT2AMAPT | |
| SCHEMBL4383820 | 0.85 | JAK2 (1.00) | JAK2JAK3MEN1KMT2AKDM4E | |
| SCHEMBL5472823 | 0.83 | ADORA1 (0.57) | JAK2JAK3MEN1KMT2AKDM4E | |
| SCHEMBL5472470 | 0.83 | ADORA3 (0.65) | JAK2JAK3CAMK2DMAPK8MAPK10 | |
| SCHEMBL5472976 | 0.82 | PIK3CA (0.59) | JAK2KDM4EMAPTCAMK2DMAPK8 | |
| SCHEMBL19706531 | 0.82 | NPC1 (0.71) | JAK2JAK3MEN1KMT2AKDM4E | |
| SCHEMBL4378143 | 0.81 | JAK2 (0.90) | JAK2JAK3MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | JAK2 2119/4885JAK3 3269/4885MEN1 2400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.