Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | DKK1 | O94907 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PRKCB | P05771 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | BCR | P11274 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.54 |
| ▸ | PRKCH | P24723 | 1/20 | 0.54 |
| ▸ | PRKCI | P41743 | 1/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465449 | 0.88 | PIK3CA (0.58) | SIRT2ADORA1PRKD3ABL1PRKCG | |
| SCHEMBL5470852 | 0.86 | ADORA1 (0.69) | ADORA1GSK3BPRKD3ABL1PRKCG | |
| SCHEMBL5472823 | 0.83 | ADORA1 (0.57) | ADORA1GSK3BPRKD3ABL1PRKCG | |
| SCHEMBL5473232 | 0.83 | DYRK1A (0.63) | ADORA1PRKD3ABL1PRKCGPRKCB | |
| SCHEMBL5472470 | 0.83 | ADORA3 (0.65) | ADORA1PRKD3ABL1PRKCGPRKCB | |
| SCHEMBL5472976 | 0.82 | PIK3CA (0.59) | ADORA1GSK3BJAK2CAMK2D | |
| SCHEMBL5462697 | 0.82 | ALDH1A1 (0.58) | SIRT2ADORA1GSK3BPRKD3ABL1 | |
| SCHEMBL5466020 | 0.82 | RAB9A (0.67) | SIRT2DKK1GSK3BABL1PDGFRB | |
| SCHEMBL5465855 | 0.82 | HDAC1 (0.67) | ADORA1ABL1BCRPRKCAJAK2 | |
| SCHEMBL5472892 | 0.80 | JAK2 (0.76) | ADORA1JAK2CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | SIRT2 1809/4885ADORA1 134/4885DKK1 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.