Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.37 |
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474590 | 0.96 | DRD2 (0.42) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5470649 | 0.95 | DRD2 (0.42) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5462896 | 0.85 | DRD2 (0.44) | HTR1ADRD2HTR2AHTR7ADRA1A | |
| SCHEMBL5481441 | 0.85 | DRD2 (0.46) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5461891 | 0.85 | HTR7 (0.39) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5468007 | 0.84 | HTR7 (0.51) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5481421 | 0.83 | HTR7 (0.47) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5473527 | 0.81 | HTR2A (0.44) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5468109 | 0.81 | HTR2A (0.43) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL5471292 | 0.79 | DRD2 (0.41) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | claimed |
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | HTR1A 3/4885DRD2 64/4885HTR2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.