Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865235 | 0.85 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10422810 | 0.81 | ALDH1A1 (0.48) | CYP4F2CYP4A11ALDH1A1LMNACYP1A2 | |
| SCHEMBL195662 | 0.80 | CYP4F2 (0.56) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9416752 | 0.80 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6507050 | 0.80 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL788715 | 0.77 | ALDH1A1 (0.46) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL16301154 | 0.76 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10586858 | 0.76 | CYP4F2 (0.46) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1785998 | 0.76 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 | |
| SCHEMBL2036323 | 0.76 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61106557-A | — | — | None | — | — | JP | disclosed |
| EP-4365162-A2 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | Intervet International B.V. (NL) | 2024-05-08 | — | — | EP | disclosed |
| US-20240051943-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | INTERVET INC. (US) | 2024-02-15 | — | — | US | disclosed |
| EP-4263528-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | Intervet International B.V. (NL) | 2023-10-25 | — | — | EP | disclosed |
| CN-116635370-A | Process for preparing N- (bis (4-methoxyphenyl) methyl) -6-oxo-2- (pyridazin-3-yl) -1, 6-dihydropyrimidine-5-carboxamide | 英特维特国际股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022136206-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | INTERVET INTERNATIONAL B.V. (NL) | 2022-06-30 | — | — | WO | disclosed |
| US-20070249862-A1 | Process for the Production of Polyisocyanate/Polysilicic Acid Based Resins with Widely Variable Processability and Setting Periods | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2007-10-25 | — | — | US | disclosed |
| US-7148232-B2 | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-12-12 | — | — | US | disclosed |
| EP-1380587-B1 | Oxazolo, thiazolo and selenazolo [4,5-c]naphthyridine-4-amines and analogs thereof | 3M INNOVATIVE PROPERTIES CO (US) | 2006-03-15 | — | — | EP | disclosed |
| US-20050026943-A1 | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY | 2005-02-03 | — | — | US | disclosed |
| US-20020072528-A1 | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY | 2002-06-13 | — | — | US | disclosed |
| US-6323200-B1 | THE COMPOUNDS ARE IMMUNOMODULATORS AND INDUCE CYTOKINE BIOSYNTHESIS, INCLUDING INTERFERON AND/OR TUMOR BIOSYNTHESIS, NECROSIS FACTOR, AND INHIBIT THE T-HELPER-TYPE 2 IMMUNE RESPONSE. | 3M INNOVATIVE PROPERTIES COMPANY | 2001-11-27 | — | — | US | disclosed |
| EP-1100802-A1 | OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF | 3M Innovative Properties Company (US) | 2001-05-23 | — | — | EP | disclosed |
| US-6110929-A | IMMUNOMODULATORS WHICH INDUCE CYTOKINE BIOSYNTHESIS, INCLUDING INTERFERON AND/OR TUMOR BIOSYNTHESIS, NECROSIS FACTOR AND INHIBIT T-HELPER-TYPE 2 IMMUNE RESPONSE; FOR TREATMENT OF VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-08-29 | — | — | US | disclosed |
| WO-2000006577-A1 | OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| CN-1025617-C | Process for preparing pyrimidine derivatives and pharmaceutically acceptable salts thereof | MITSUI PHARMACEUTICALS (JP) | 1994-08-10 | — | — | CN | disclosed |
| CN-1079742-A | Prepare the pyrimidine derivatives and the method for available salt pharmaceutically thereof | MITSUI PHARMACEUTICALS (JP) | 1993-12-22 | — | — | CN | disclosed |
| CN-1032004-A | Pyrimidine derivatives and pharmaceutically acceptable salts thereof | MITSUI PHARMACEUTICALS (JP) | 1989-03-29 | — | — | CN | disclosed |
| JP-S61106557-A | 1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID DERIVATIVE | MORISHITA SEIYAKU KK | 1986-05-24 | — | — | JP | disclosed |
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072528-A1 | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof | IFNG, THPO, IL2 | CYP4F2 363/4885CYP4A11 892/4885ALDH1A1 2933/4885 |
| US-20050026943-A1 | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof | IFNG, IL2, IRF3 | CYP4F2 377/4885CYP4A11 747/4885ALDH1A1 2667/4885 |
| US-20240051943-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | DPYD, TPMT, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CYP4F2 108/4885CYP4A11 841/4885ALDH1A1 696/4885 |
| US-20070249862-A1 | Process for the Production of Polyisocyanate/Polysilicic Acid Based Resins with Widely Variable Processability and Setting Periods | ME1, PICALM, CA6 | CYP4F2 616/4885CYP4A11 932/4885ALDH1A1 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.