Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 15/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486513 | 0.84 | KDM4E (0.43) | GRIK1KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5468641 | 0.81 | ABL1 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL11603313 | 0.81 | GRIK1 (0.62) | GRIK1KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28677897 | 0.80 | KDM5A (0.69) | KDM4EALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL14521237 | 0.79 | GRIK1 (0.60) | GRIK1KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22858729 | 0.79 | ACLY (0.51) | GRIK1KDM4E | |
| SCHEMBL1321725 | 0.78 | KDM4E (0.63) | GRIK1KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29183052 | 0.78 | GRIK1 (0.68) | GRIK1KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17627435 | 0.78 | GRIK1 (0.58) | GRIK1KDM4EALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL11604092 | 0.76 | GRIK1 (0.57) | GRIK1KDM4EALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | GRIK1 1755/4885KDM4E 3789/4885ALDH1A1 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.