Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471460 | 0.89 | FOLH1 (0.54) | RNPEPFOLH1LDHALDHBTDP1 | |
| SCHEMBL5456827 | 0.88 | RNPEP (0.46) | RNPEPFOLH1EPHX1LDHALDHB | |
| SCHEMBL7554203 | 0.85 | — | — | |
| SCHEMBL1679967 | 0.85 | RNPEP (0.50) | RNPEPFOLH1EPHX1CA1CA2 | |
| SCHEMBL19042804 | 0.83 | — | — | |
| SCHEMBL5971223 | 0.83 | — | — | |
| SCHEMBL5470071 | 0.80 | RNPEP (0.38) | RNPEPFOLH1EPHX1LDHALDHB | |
| SCHEMBL18756515 | 0.79 | RNPEP (0.68) | RNPEPFOLH1ALDH1A1LMNAALOX15 | |
| SCHEMBL7098138 | 0.79 | — | — | |
| SCHEMBL8556461 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | claimed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | claimed |
| EP-1570834-A1 | Composition for permanently deforming hair containing at least a dicarboxydithiol | L'OREAL (FR) | 2005-09-07 | — | — | EP | claimed |
| US-6660863-B2 | Reacting an cycloheptatriene nitrile compound with nortropane compound | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-12-09 | — | — | US | claimed |
| US-20030109708-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS CO., LTD. | 2003-06-12 | — | — | US | claimed |
| US-20010020096-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2001-09-06 | — | — | US | claimed |
| EP-1127887-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-08-29 | — | — | EP | claimed |
| US-20070134185-A1 | Use of dithiols in a hair-perming composition | L'OREAL S.A. (FR) | 2007-06-14 | — | — | US | disclosed |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | MALLE GERARD | 2007-01-11 | — | — | US | disclosed |
| US-20060189567-A1 | Compound having affinity with calcified tissue | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1609797-A1 | COMPOUND HAVING AFFINITY WITH CALCIFIED TISSUE | Nihon Medi-Physics Co., Ltd. (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | L'OREAL S.A. (FR) | 2005-09-15 | — | — | US | disclosed |
| EP-1570834-A1 | Composition for permanently deforming hair containing at least a dicarboxydithiol | L'OREAL (FR) | 2005-09-07 | — | — | EP | disclosed |
| US-6660863-B2 | Reacting an cycloheptatriene nitrile compound with nortropane compound | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| US-20030186845-A1 | Compositions for preventing urinary calculus | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| US-6596868-B2 | Reacting a cycloheptatriene derivative with a primary amine or ammonia in the presence of a base | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-1323433-A1 | COMPOSITIONS FOR PREVENTING URINARY CALCULUS | Nihon Medi-Physics Co., Ltd. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-20030109708-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS CO., LTD. | 2003-06-12 | — | — | US | disclosed |
| US-20010020096-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1127887-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070134185-A1 | Use of dithiols in a hair-perming composition | DSG1, DSC1, DUS2 | RNPEP 3205/4885FOLH1 435/4885EPHX1 2315/4885 |
| US-20050201964-A1 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | RNPEP 3213/4885FOLH1 2078/4885EPHX1 1566/4885 |
| US-20070009462-A9 | Composition to permanently reshape the hair containing at least one dicarboxydithiol | NR5A1, SRD5A2, HRH3 | RNPEP 3213/4885FOLH1 2078/4885EPHX1 1566/4885 |
| US-20060189567-A1 | Compound having affinity with calcified tissue | SLC7A1, MBNL1, SHBG | RNPEP 546/4885FOLH1 1422/4885EPHX1 4409/4885 |
| US-20030109708-A1 | Process for synthesizing anhydroecgonine derivative | CES2, NPR1, OPRL1 | RNPEP 433/4885FOLH1 2021/4885EPHX1 1250/4885 |
| US-20010020096-A1 | Process for synthesizing anhydroecgonine derivative | CES2, NPR1, OPRL1 | RNPEP 433/4885FOLH1 2021/4885EPHX1 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.