Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470517 | 0.76 | LMNA (0.34) | PTGS2ALDH1A1IGF1RSRCAXL | |
| Hydrochloric Acid SCHEMBL5473450 | 0.75 | LMNA (0.33) | PTGS2ALDH1A1IGF1RSRCAXL | |
| SCHEMBL5473449 | 0.75 | IGF1R (0.33) | PTGS2ALDH1A1IGF1RSRCAXL | |
| SCHEMBL15055376 | 0.70 | PTGS2 (0.31) | PTGS2SMN1; SMN2 | |
| SCHEMBL9078218 | 0.69 | — | — | |
| SCHEMBL9448464 | 0.69 | VCAM1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9448447 | 0.69 | EPAS1 (0.38) | PTGS2ALDH1A1SMN1; SMN2EPAS1HPGD | |
| SCHEMBL9657374 | 0.68 | HPD (0.36) | PTGS2ALDH1A1 | |
| SCHEMBL4780550 | 0.68 | ALDH1A1 (0.43) | ALDH1A1IGF1RSRCAXLPTK2 | |
| SCHEMBL22090249 | 0.66 | EPAS1 (0.36) | ALDH1A1EPAS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34423-E | For producing 4-benzoyl-5-hydroxypyrazoles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-RE34408-E | Reacting carbon monoxide with a 5-hydroxy pyrazole and a substituted benzene | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0344775-B1 | PROCESS FOR PRODUCING 4-BENZOYL-5-HYDROXYPYRAZOLES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5087724-A | For herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| US-4942246-A | CARBONYLATION, CONDENSATION, HERBICIDES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-07-17 | — | — | US | disclosed |
| EP-0344775-A1 | Process for producing 4-benzoyl-5-hydroxypyrazoles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-12-06 | — | — | EP | disclosed |