SCHEMBL547205

SCHEMBL547205

NCCCC(N)(CCN)CCCN

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.38
ODC1 P11926 2/20 0.36
CA12 O43570 4/20 0.35
CA2 P00918 4/20 0.35
CA4 P22748 4/20 0.35
CA6 P23280 4/20 0.35
CA5A P35218 4/20 0.35
CA7 P43166 4/20 0.35
CA9 Q16790 4/20 0.35
CA14 Q9ULX7 4/20 0.35
CA5B Q9Y2D0 4/20 0.35
CA1 P00915 3/20 0.35
CA3 P07451 3/20 0.35
LMNA P02545 2/20 0.35
BLM P54132 2/20 0.35
TSHR P16473 2/20 0.35
DNM1 Q05193 1/20 0.35
FDPS P14324 1/20 0.35
PDE3A Q14432 1/20 0.35
CASP2 P42575 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL817856 1.00 NFKB1 (0.38) NFKB1ODC1CA12CA2CA4
SCHEMBL816414 0.93 NFKB1 (0.43) NFKB1ODC1CA12CA2CA4
Hydrochloric Acid SCHEMBL16398251 0.90 NFKB1 (0.40) NFKB1ODC1CA12CA2CA4
Water SCHEMBL30354056 0.90 NFKB1 (0.40) NFKB1ODC1CA12CA2CA4
SCHEMBL817593 0.88 DNM1 (0.47) NFKB1CA12CA2CA4CA6
SCHEMBL5366358 0.87 NFKB1 (0.47) NFKB1ODC1CA12CA2CA4
SCHEMBL2357721 0.87 NFKB1 (0.47) NFKB1ODC1CA12CA2CA4
SCHEMBL11262880 0.87 ODC1 (0.30) ODC1
SCHEMBL318005 0.86 LMNA (0.32) CA12CA6CA7CA9CA14
SCHEMBL7093120 0.84 DNM1 (0.50) NFKB1CA12CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911300-A1 DRUG DELIVERY SYSTEM The University of Birmingham (GB) 2021-11-24 EP claimed
EP-3077006-B1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY WU NIAN (US) 2020-08-19 EP claimed
WO-2020148556-A1 DRUG DELIVERY SYSTEM THE UNIVERSITY OF BIRMINGHAM (GB) 2020-07-23 WO claimed
EP-3478249-A1 STABLE MICROCAPSULE COMPOSITIONS International Flavors & Fragrances Inc. (US) 2019-05-08 EP claimed
US-10064954-B2 Polymer-cyclodextrin-lipid conjugates LIPOSEUTICALS INC 2018-09-04 US claimed
US-9914882-B2 Reverse emulsion breaker polymers ECOLAB USA INC. (US) 2018-03-13 US claimed
WO-2018006089-A1 STABLE MICROCAPSULE COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2018-01-04 WO claimed
US-20160375150-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES LIPOSEUTICALS INC 2016-12-29 US claimed
EP-3077006-A1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY Wu, Nian (US) 2016-10-12 EP claimed
WO-2016144613-A1 REVERSE EMULSION BREAKER POLYMERS ECOLAB USA INC. (US) 2016-09-15 WO claimed
US-8003705-B2 In situ formation of slowly biodegradable materials; reaction between precursors having electrophilic and nucleophilic functionality; enzymatic and hydrolysis resistance; controlled drug delivery agents, postoperative adhesion prevention, medical device coatings, wound dressings, surgical sealants; kits INCEPT LLC (US) 2011-08-23 US claimed
EP-2196193-A1 Hydrogels suitable for use in polyp removal Tyco Healthcare Group LP (US) 2010-06-16 EP claimed
US-20090324721-A1 Hydrogels Suitable For Use In Polyp Removal TYCO HEALTHCARE GROUP LP 2009-12-31 US claimed
US-20080260802-A1 Biocompatible hydrogels made with small molecule precursors OCULAR THERAPEUTIX, INC. 2008-10-23 US claimed
EP-1436374-A1 BENEFIT AGENT DELIVERY SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2004-07-14 EP claimed
WO-2003033636-A1 BENEFIT AGENT DELIVERY SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2003-04-24 WO claimed
EP-1246899-A1 PRO-PERFUME COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2002-10-09 EP claimed
CN-1321187-A Laundry and cleaning compositions PROCTER & GAMBLE (US) 2001-11-07 CN claimed
WO-2001051599-A1 PRO-PERFUME COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2001-07-19 WO claimed
WO-2001004084-A1 PROCESS FOR MAKING AMINE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2001-01-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10064954-B2 Polymer-cyclodextrin-lipid conjugates CETP, FABP4, PLIN3 NFKB1 3801/4885ODC1 688/4885CA12 1434/4885
US-20160375150-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES CETP, FADS2, FABP4 NFKB1 3877/4885ODC1 398/4885CA12 1995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.