SCHEMBL547223

SCHEMBL547223

O=C(O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MME P08473 4/20 0.67
L3MBTL1 Q9Y468 1/20 0.66
NPSR1 Q6W5P4 1/20 0.65
NAALAD2 Q9Y3Q0 2/20 0.63
ACE2 Q9BYF1 3/20 0.59
ACE P12821 2/20 0.59
CPA1 P15085 2/20 0.59
FPR2 P25090 5/20 0.58
PTPN1 P18031 1/20 0.58
FOLH1 Q04609 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547222 1.00 MME (0.67) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL1696507 1.00 MME (0.67) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL18180178 0.88 NAALAD2 (0.78) MMEL3MBTL1NPSR1NAALAD2FPR2
SCHEMBL19969196 0.88 NAALAD2 (0.78) MMEL3MBTL1NPSR1NAALAD2FPR2
SCHEMBL10795720 0.87 MME (0.62) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL5841327 0.86 MME (0.65) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL1012053 0.85 MME (0.63) MMEL3MBTL1NPSR1NAALAD2ACE2
Afalanine SCHEMBL331330 0.85 CTSS (0.65) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL4028404 0.85 ALDH1A1 (0.57) MMEL3MBTL1
SCHEMBL17785192 0.85 MME (0.68) MMEL3MBTL1NPSR1NAALAD2ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116162255-B Charge-convertible dendrimer and preparation method thereof 东莞理工学院 2024-07-09 CN claimed
EP-4274838-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BicycleTx Limited (GB) 2023-11-15 EP claimed
EP-4199968-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF Ambrx, Inc. (US) 2023-06-28 EP claimed
EP-4117732-A1 INTERLEUKIN-2 POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF Ambrx, Inc. (US) 2023-01-18 EP claimed
WO-2022148974-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LIMITED (GB) 2022-07-14 WO claimed
WO-2022040596-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2022-02-24 WO claimed
EP-3923991-A1 COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES Ambrx, Inc. (US) 2021-12-22 EP claimed
WO-2021183832-A1 INTERLEUKIN-2 POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF AMBRX, INC. (US) 2021-09-16 WO claimed
EP-3844188-A1 ANTI-CD3 ANTIBODY FOLATE BIOCONJUGATES AND THEIR USES Ambrx, Inc. (US) 2021-07-07 EP claimed
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2021-05-13 US claimed
EP-2249865-A2 BREAKING IMMUNOLOGICAL TOLERANCE WITH A GENETICALLY ENCODED UNNATURAL AMINO ACID The Scripps Research Institute (US) 2010-11-17 EP claimed
WO-2009099672-A2 BREAKING IMMUNOLOGICAL TOLERANCE WITH A GENETICALLY ENCODED UNNATURAL AMINO ACID THE SCRIPPS RESEARCH INSTITUTE (US) 2009-08-13 WO claimed
EP-2081602-A2 TOXIN PEPTIDE THERAPEUTIC AGENTS Amgen Inc. (US) 2009-07-29 EP claimed
WO-2008088422-A2 TOXIN PEPTIDE THERAPEUTIC AGENTS AMGEN INC. (US) 2008-07-24 WO claimed
EP-1793843-A1 MACROCYCLIC SH2 DOMAIN BINDING INHIBITORS Government of the United States of America, Represented by the Secretary, Department of Health and Human Services (US) 2007-06-13 EP claimed
WO-2006039527-A1 MACROCYCLIC SH2 DOMAIN BINDING INHIBITORS GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-04-13 WO claimed
WO-2006017619-A2 RECEPTOR-BINDING CYCLIC PEPTIDES AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-02-16 WO claimed
US-20060029544-A1 Receptor-binding cyclic peptides and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) 2006-02-09 US claimed
EP-0521827-A1 Pharmacological active hydrazin derivatives and process for their preparation CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
EP-0009777-B1 RETINOIC- AND 7,8-DEHYDRO-RETINOIC-ACID-N-(CARBOXY)PHENYL AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BASF Aktiengesellschaft (DE) 1982-05-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR BMP2, BMP4, BMP6 MME 2617/4885L3MBTL1 4015/4885NPSR1 2141/4885
US-20060029544-A1 Receptor-binding cyclic peptides and methods of use ITGB3, ITGB5, ITGA5 MME 3723/4885L3MBTL1 2786/4885NPSR1 372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.