SCHEMBL669541

SCHEMBL669541

O=c1oc2ccccc2c(Br)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.58
NQO1 P15559 7/20 0.56
ALDH1A1 P00352 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
ABCB11 O95342 1/20 0.56
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.56
CYP2C19 P33261 1/20 0.56
PDE4D Q08499 1/20 0.56
PCSK7 Q16549 1/20 0.56
GPR35 Q9HC97 1/20 0.56
CA12 O43570 2/20 0.53
CA9 Q16790 2/20 0.53
VKORC1 Q9BQB6 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30050788 1.00 KDM4E (0.58) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL669540 0.85 KDM4E (0.62) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL29379994 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL5472418 0.82 HSD17B10 (0.54) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL29872 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL7737431 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL8701572 0.80 KDM4E (0.67) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL30153359 0.77 KDM4E (0.73) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL5532851 0.77 KDM4E (0.73) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL31178946 0.77 GAA (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3008201-A1 METHODS, KITS, AND SYSTEMS FOR MULTIPLEXED DETECTION OF TARGET MOLECULES AND USES THEREOF The General Hospital Corporation (US) 2016-04-20 EP claimed
WO-2014200767-A1 METHODS, KITS, AND SYSTEMS FOR MULTIPLEXED DETECTION OF TARGET MOLECULES AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2014-12-18 WO claimed
EP-4665868-A2 METHODS FOR MULTIPLEXED IMAGING AND DETECTION OF TARGETS President and Fellows of Harvard College (US) 2025-12-24 EP disclosed
US-20250121055-A1 INTERFERON- INDUCING COMPLEXES AND RNA DUPLEXES AND METHODS OF USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-04-17 US disclosed
WO-2025029623-A2 LIGHT-TRIGGERED POLYMER-NALOXONE CONJUGATE FOR OPIOID REVERSAL THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-02-06 WO disclosed
WO-2025022355-A1 METHODS OF BARCODING SINGLE CELLS AND CELLULAR SUBPOPULATIONS AND USES THEREOF COSYNE THERAPEUTICS LIMITED (GB) 2025-01-30 WO disclosed
US-12140520-B2 Nanosensors and use thereof NanoMosaic INC. (US) 2024-11-12 US disclosed
EP-4189114-B1 HIGH THROUGHPUT ANALYSIS OF FIXED CELLS SINGLERON BIOTECHNOLOGIES INC (US) 2024-09-18 EP disclosed
EP-4395788-A1 INTERFERON- INDUCING COMPLEXES AND RNA DUPLEXES AND METHODS OF USE President And Fellows Of Harvard College (US) 2024-07-10 EP disclosed
EP-3914734-B1 COMPOSITIONS AND METHOD FOR SYNTHESIZING NUCLEIC ACIDS HARVARD COLLEGE (US) 2024-03-13 EP disclosed
US-20230417756-A1 SENSORS FOR UNBIASED PROTEOMIC STUDIES, METHOD OF MANUFACTURE AND USE THEREOF NanoMosaic INC. 2023-12-28 US disclosed
US-20150266809-A1 DOUBLE CAGED GABA COMPOUNDS, BIS-CNB-GABA THE TRUSTEES OF PRINCETON UNIVERSITY 2015-09-24 US disclosed
WO-2014200767-A1 METHODS, KITS, AND SYSTEMS FOR MULTIPLEXED DETECTION OF TARGET MOLECULES AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2014-12-18 WO disclosed
US-20140031285-A1 PHOTODEGRADABLE GROUPS FOR TUNABLE POLYMERIC MATERIALS NATIONAL SCIENCE FOUNDATION 2014-01-30 US disclosed
US-8343710-B1 Photodegradable groups for tunable polymeric materials THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-01-01 US disclosed
WO-2012024558-A2 LIGHT MEDIATED REGULATION OF PROTEIN DIMERIZATION THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2012-02-23 WO disclosed
US-20110178281-A1 Photocleavable Linker Methods and Compositions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2011-07-21 US disclosed
US-7923562-B2 Photocleavable linker methods and compositions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-04-12 US disclosed
US-20100022761-A1 PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2010-01-28 US disclosed
JP-2007319064-A METHOD FOR EXPRESSING PROTEIN SITE-SPECIFICALLY INTRODUCED MODIFIED AMINO ACID JAPAN SCIENCE & TECHNOLOGY AGENCY 2007-12-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266809-A1 DOUBLE CAGED GABA COMPOUNDS, BIS-CNB-GABA GABRB2, GABRB3, GABRB1 KDM4E 1522/4885NQO1 4013/4885ALDH1A1 2034/4885
US-20110178281-A1 Photocleavable Linker Methods and Compositions NSUN2, RNGTT, METTL16 KDM4E 254/4885NQO1 412/4885ALDH1A1 1111/4885
US-20100022761-A1 PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS NSUN2, RNGTT, METTL16 KDM4E 254/4885NQO1 412/4885ALDH1A1 1111/4885
US-20140031285-A1 PHOTODEGRADABLE GROUPS FOR TUNABLE POLYMERIC MATERIALS ANXA5, ANXA2, ANXA7 KDM4E 3617/4885NQO1 4885/4885ALDH1A1 3754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.