Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.59 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.54 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465449 | 0.91 | PIK3CA (0.58) | PIK3CAADORA3TMIGD3KDM4EMAPT | |
| SCHEMBL5470852 | 0.87 | ADORA1 (0.69) | ADORA3KDM4EMAPTNPC1RAB9A | |
| SCHEMBL5473232 | 0.86 | DYRK1A (0.63) | ADORA3MAPTNPC1RAB9AJAK2 | |
| SCHEMBL5465855 | 0.84 | HDAC1 (0.67) | PIK3CAKDM4EMAPTJAK2PIK3CG | |
| SCHEMBL5462749 | 0.84 | SCN10A (0.54) | PIK3CAJAK2ADORA1GSK3BCAMK2D | |
| SCHEMBL5472470 | 0.83 | ADORA3 (0.65) | ADORA3JAK2MAPK8ADORA1CAMK2D | |
| SCHEMBL5472823 | 0.83 | ADORA1 (0.57) | KDM4EMAPTNPC1RAB9AJAK2 | |
| SCHEMBL5472892 | 0.82 | JAK2 (0.76) | KDM4EMAPTJAK2MAPK8ADORA1 | |
| SCHEMBL5459991 | 0.82 | PRKCA (0.52) | PIK3CAADORA3CDKN1ANPC1PIK3CG | |
| SCHEMBL5465350 | 0.82 | SIRT2 (0.68) | JAK2ADORA1GSK3BCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | PIK3CA 4595/4885ADORA3 187/4885TMIGD3 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.