Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.84 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.84 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481289 | 0.92 | PTGS2 (1.00) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| Dioxane SCHEMBL5472966 | 0.91 | PTGS2 (0.88) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| Water SCHEMBL5477391 | 0.91 | PTGS2 (1.00) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| SCHEMBL11925221 | 0.83 | PTGS2 (0.75) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| SCHEMBL28922237 | 0.83 | PTGS2 (0.82) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| SCHEMBL5073588 | 0.82 | PTGS2 (0.81) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| SCHEMBL5071844 | 0.82 | PTGS2 (0.81) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| Ethyl Acetate SCHEMBL5483783 | 0.81 | PTGS2 (0.79) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| SCHEMBL5071829 | 0.81 | PTGS2 (0.78) | PTGS2MT-CO2NR4A2PTGS1CA12 | |
| SCHEMBL5071029 | 0.80 | PTGS2 (0.77) | PTGS2MT-CO2NR4A2PTGS1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093539-A1 | N-hydroxy-4-(3-pheyl-5-methyl-isoxazole-4-yl)-benzenesulfonate solvates | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093539-A1 | N-hydroxy-4-(3-pheyl-5-methyl-isoxazole-4-yl)-benzenesulfonate solvates | ADH1A, ADH1C, ADH5 | PTGS2 154/4885MT-CO2 1354/4885NR4A2 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.