Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 10/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 9/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.52 |
| ▸ | MST1R | Q04912 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465912 | 0.84 | NPSR1 (0.49) | CDK9CCNT1NPSR1AURKAMAP4K4 | |
| SCHEMBL5473356 | 0.82 | MEN1 (0.51) | PIK3CDSLC40A1ALDH1A1SCN9AKMT2A | |
| SCHEMBL5472845 | 0.82 | NPSR1 (0.46) | CDK9CCNT1NPSR1SLC40A1ALDH1A1 | |
| SCHEMBL5465058 | 0.82 | NPSR1 (0.46) | CDK9CCNT1NPSR1AURKAMAP4K4 | |
| SCHEMBL5471322 | 0.78 | L3MBTL1 (0.46) | CDK9AURKAMAP4K4ABL1LCK | |
| SCHEMBL5459991 | 0.78 | PRKCA (0.52) | ABL1AURKBKMT2ALMNATSHR | |
| SCHEMBL38666234 | 0.74 | NPSR1 (0.67) | NPSR1SLC40A1ALDH1A1LMNATSHR | |
| SCHEMBL5472490 | 0.74 | ALDH1A1 (0.52) | CDK9CCNT1ALDH1A1SCN9AKMT2A | |
| SCHEMBL5464963 | 0.74 | PDE4A (0.42) | CDK9CCNT1AURKAMAP4K4ABL1 | |
| SCHEMBL5472495 | 0.74 | AKT1 (0.44) | CDK9CCNT1NPSR1ALDH1A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | CDK9 2875/4885CCNT1 1660/4885NPSR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.